SIMPONI ARIA

Generic Name: Golimuumab

Medication Guide: PDF Download

Administration Guide: PDF Download

​​

Basic Step-by-Step:   

 

**ALWAYS establish patent IV access and flush PRIOR to mixing medication**

MIXING

​

• Simponi Aria comes in single-use 50mg vials which yield a liquid volume of 4ml.

• The solution should appear colorless to light yellow. The solution may develop a few fine translucent particles as it is a protein.  Do not use if opaque particles, discoloration, or other foreign particles are present.

• Determine the number of vials needed to make up the dose per the orders.

• Obtain a clear/clean space to prepare the medication.

• Be sure all the necessary supplies are available to complete infusion from beginning to end. 

  • You will need IV start/port access supplies, a syringe and needle, 100 ml bag of Normal Saline for dilution, tubing (gravity tubing or pump tubing if using a pump), low protein-binding filter (0.22 microns or less in size).

• Draw up the prescribed dose in a syringe.  The medication will need to be further diluted with Normal Saline.

• Remove the volume of Normal Saline from the 100 ml infusion bag equal to the volume of the total volume of Simponi Aria.

  • For example, if you are drawing up 7ml of medication, you would remove 7ml of NS from the bag

  • The total volume of Normal Saline and the medication will equal 100 ml.

• Inject the medication into the bag of Normal Saline. Gently mix. DO NOT shake.

• Spike the IV bag with the pump or gravity tubing provided.

​

ADMINISTRATION

​

1. Take and document baseline vitals. Document basic assessment.

2. Infuse Simponi Aria over 30 minutes or per order.

3. Take and document vitals 15 minutes into the infusion and 5 minutes post-infusion.

4. Document lot numbers and expiration dates for all vials used.

5. Disconnect patient, flush line, and remove IV, placing a pressure bandage at site. 

6. Clean and dispose of used supplies.