ADAKVEO (IV)

crizanlizumab-tmca

ALWAYS establish patent IV access and flush PRIOR to mixing medication

ALWAYS establish IV access prior to mixing any meds

ALWAYS make sure you have everything you need to complete infusion before you begin

ALWAYS confirm your medication dose against the medication label and orders

ALWAYS reach out to us first (not the Pharmacy) with any questions

NEVER tell a Pt you have not given a particular medication before

Obtain a clear/clean space to prepare the ADAKVEO
Be sure all the necessary supplies are available to complete infusion from beginning to end. You will need: IV start supplies, bag of 0.9% Sodium Chloride or 5% Dextrose; syringes and needles, IV tubing with 0.2-micron inline filter
Remove a volume of 0.9% Sodium Chloride Injection or 5% Dextrose Injection from the infusion bag/container that is equal to the required volume of ADAKVEO solution
Withdraw the necessary amount of ADAKVEO solution and dilute by adding to the infusion bag/container containing 0.9% Sodium Chloride Injection or 5% Dextrose Injection
- The volume of ADAKVEO added to the infusion bag/container should not exceed 96 mL
Gently invert the infusion bag to mix the diluted solution
- DO NOT SHAKE

Take baseline vitals and document basic assessment
Administer ADAKVEO diluted solution by intravenous infusion over a period of 30 minutes
Monitor patient for any adverse reactions
Record vitals every 15 minutes after infusion start, AND 5-10 minutes post infusion
Record lot numbers and expiration dates for vials used
After administration of ADAKVEO, flush the line with at least 25 mL of 0.9% Sodium Chloride Injection or 5% Dextrose Injection
Disconnect patient and remove IV
- Place pressure bandage at site
Clean and dispose of used supplies

HCP Website: Adakveo

Prescribing Info: Adakveo PI