**ALWAYS establish patent IV access and flush PRIOR to mixing medication**
Pharmacy specific orders / instructions always supersede the Agency guidance provided below. If in doubt, do not guess, call our office, or tag @TeamHelp-CareCoordination and ask for Clinical Support.
ALWAYSÂ establish IV access prior to mixing any meds
ALWAYSÂ make sure you have everything you need to complete infusion before you begin
ALWAYSÂ confirm your medication dose against the medication label and orders
ALWAYSÂ reach out to us first (not the Pharmacy) with any questions
NEVERÂ tell a Pt you have not given a particular medication before
MIXING
Remember: Even if patient has drug out when you arrive, you MUST still verify that you have the correct dose to give. ALWAYS check the dose against the orders. If there is any confusion about the dose, reach out to the Agency before proceeding.
Obtain a clear/clean space to prepare medication
Be sure all the necessary supplies are available to complete infusion from beginning to end
Verify orders, check medication expiration date
Factor is rarely dispensed in the exact dose as order, usually it is a range, with +/- 10% range being the most common
Verify the dose is within the ordered range
Obtain access with NS flush attached and secure
Never open or mix medications before obtaining access
Access may be by butterfly or by PIV
 Mix meds following manufacturer directions.
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ADMINISTRATION
Take baseline vitals and document basic assessment
Administer factor as directed by orders (normally Slow IV push over 3-5 minutes)
Record vitals 5-10 minutes post infusion
Record lot numbers and expiration dates for vials used
Disconnect patient, flush line, and remove. Place pressure bandage at site.
Clean and dispose of used supplies
Documentation
DOCUMENTÂ the EXACTÂ dose given (not the dose ordered)
Document the site and type of access
Document how patient tolerated infusion
Document if patient has any signs of a bleed, document what the site looks like and any pain relief methods the patient is using
Document how many doses of Factor are in the home – maintenance and prn
TEACHING
IF orders allow for RN to teach pt/family to administer factor teaching should focus on:
General knowledge of hemophilia
Recognition of bleeds and common complications
Dosage calculation u Preparation and storage
Aseptic techniques
Performing venipuncture (or access of central venous catheter)
Administration technique
Record keeping, proper storage and disposal of needles/sharps, and handling of blood spills.
ADDITIONAL INFO
HCP Website:Â HelmsHomecare-PolicyÂ
In-Service:Â HHC In-service for Coagulant Blood Products for Bleeding Disorders
Video: Understanding-Hemophilia
Coagulant Blood Product Brands
Advate:Â AdvateHCP
Adynovate:Â AynovateHCPÂ
Alphanate: AlphanateHCPÂ Alprolix: AlprolixHCP ; Alprolix-Instructions-for-use
Altuviio: AltuviiioHCP; Altuviiio-PI; ALTUVIIIO video; Altuviiio-Instructions-for-use
Benefix: Benefix-HCPÂ ; Benefix-Instructions-for-use ; Â Benefix-Infusion-Video
Eloctate:  Eloctate ; Eloctate- Video
Esperoct:Â ExperoctHCP
Eloctate:  Eloctate ; Eloctate- Video
Esperoct:Â ExperoctHCP
Hemlibra:Â HemlibraHCP
Humate:Â HumateHCP
Idelvion:Â IdelvionHCP
Novoseven:Â NovosevenHCP
Novoeight:Â NovoeightHCP
Recombinate:Â RecombinateÂ
VonVendi:Â VonvendiHCPÂ
Xyntha:Â XynthaHCP
Wilate:Â WilateusaHCPÂ
