EVKEEZA (IV)

ALWAYS establish patent IV access and flush PRIOR to mixing medication

ALWAYS establish IV access prior to mixing any meds

ALWAYS make sure you have everything you need to complete infusion before you begin

ALWAYS confirm your medication dose against the medication label and orders

ALWAYS reach out to us first (not the Pharmacy) with any questions

NEVER tell a Pt you have not given a particular medication before

Obtain a clear/clean space to prepare Evkeeza.
Be sure all the necessary supplies are available to complete infusion from beginning to end.
- You will need IV start supplies, syringe(s), needle, bag of NS, tubing (gravity tubing or pump tubing if using a pump).
Determine the number of vials needed.
- Calculate the required Evkeeza vials based on patient’s body weight
Inspect the solution, should be clear to slightly opalescent, colorless to pale yellow.
Withdraw the required volume of Evkeeza from the vials and transfer into an IV infusion bag containing a maximum volume of 250 ml of either:
- 0.9% Sodium Chloride Injection, USP
- 5% Dextrose Injection, USP
The final concentration must be between 0.5 mg/ml and 20 mg/ml
Gently invert the infusion bag to mix. (Do not shake vigorously.)

Take baseline vitals and document basic assessment.
Spike the bag of Evkeeza & prime line.
Use an in-line or add-on 0.2-micron to 5-micron filter.
Infuse over 60 minutes.
Record vitals every 15 minutes and post infusion.
Record lot numbers and expiration dates for vials used.
After infusion completed, flush the line.
Disconnect patient, flush line, and remove IV.
- Place pressure bandage at site.
Clean and dispose of used supplies

Website: Evkeeza

Prescribing Info: Prescribing Information.pdf

Dosing and Administration: Dosing-Administration