NULOJIX (IV)

Belatacept

ALWAYS establish patent IV access and flush PRIOR to mixing medication

ALWAYS establish IV access prior to mixing any meds

ALWAYS make sure you have everything you need to complete infusion before you begin

ALWAYS confirm your medication dose against the medication label and orders

ALWAYS reach out to us first (not the Pharmacy) with any questions

NEVER tell a Pt you have not given a particular medication before

Obtain a clear/clean space to prepare the NULOJIX
Be sure all the necessary supplies are available to complete infusion from beginning to end. You will need IV start supplies, tubing with STERILE, NON-PYROGENIC, LOW-PROTEIN–BINDING FILTER (port size 0.2-1.2 μm), diluent to reconstitute, silicone-free disposable syringe that come with each vial, needles and bag of infusion fluid.
Calculate the number of NULOJIX vials needed based on the prescribed dose. Each vial contains 250 mg of belatacept lyophilized powder.
Reconstitute using either sterile water (SWF), 0.9 % sodium chloride (NS) or 5% dextrose in water (D5W). (You MUST use SILICONE-FREE disposable syringes)
Withdraw a volume of infusion fluid that is equal to the volume of the reconstituted NULOJIX solution required to provide the prescribed dose.
Using the same SILICONE-FREE disposable syringe used for reconstitution, withdraw the required amount of NULOJIX solution from the vial and inject into the infusion bag.

Take baseline vitals and document basic assessment.
Infuse over a period of 30 minutes.
Monitor patient for any adverse reactions.
Record vitals every 15 minutes after infusion start AND 5-10 minutes post infusion.
Record lot numbers and expiration dates for vials used.
Disconnect patient, flush line, and remove IV. Place pressure bandage at site.
Clean and dispose of used supplies.