**ALWAYS establish patent IV access and flush PRIOR to mixing medication**
Pharmacy specific orders / instructions always supersede the Agency guidance provided below. If in doubt, do not guess, call our office, or tag @TeamHelp-CareCoordination(Best Tag)Â and ask for Clinical Support.
ALWAYSÂ establish IV access prior to mixing any meds
ALWAYSÂ make sure you have everything you need to complete infusion before you begin
ALWAYSÂ confirm your medication dose against the medication label and orders
ALWAYSÂ reach out to us first (not the Pharmacy) with any questions
NEVERÂ tell a Pt you have not given a particular medication before
MIXING
Obtain a clear/clean space to prepare the
Be sure all the necessary supplies are available to complete infusion from beginning to end. You will need: medication, 250 ml bag of 0.9% Sodium Chloride Injection, USP or 0.45% Sodium Chloride Injections, USP, syringe and needle, IV start supplies, alcohol swabs, gauze, bandage, IV tubing with an in-line  sterile, non-pyrogenic, low protein-binding filter (pore size 0.2 micrometer)
Withdraw and discard a volume of the 0.9% Sodium Chloride Injection, USP from the 250 ml infusion bag equal to the volume of PYZCHIVA to be added
Discard 26 mL sodium chloride for each vial of PYZCHIVA needed
Withdraw the ordered dose and add to the 250 ml infusion bag
The final volume in the infusion bag should be 250 ml
Gently mix
ADMINISTRATION
Take baseline vitals and document basic assessment
Spike the bag with tubing
Infuse over at least one hour
Monitor patient for any adverse reactions
Record vital signs at baseline, every 15 minutes for the first hour, AND 5-10 minutes post infusion
Record lot numbers and expiration dates for vials used
Disconnect patient, flush line, and remove IV
Place pressure bandage at site
Clean and dispose of used supplies
ADDITIONAL INFO
HCP Website:Â Pyzchiva HCP
Prescribing Info:Â Â Â Pyzchiva PIÂ Â
Medication Guide: Â Â Pyzchiva Med Guide
Administration Guide: Â Â Pyzchiva Admin Guide
