VYJUVEK (TOPICAL)

beremagene geperpavec-svdt

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Pharmacy specific orders / instructions always supersede the Agency guidance provided below. If in doubt, do not guess, call our office, or tag @TeamHelp-CareCoordination(Best Tag) and ask for Clinical Support.

ALWAYS make sure you have everything you need to complete infusion before you begin

ALWAYS confirm your medication dose against the medication label and orders

ALWAYS reach out to us first (not the Pharmacy) with any questions

NEVER tell a Pt you have not given a particular medication before

MIXING

Obtain a clear/clean space to prepare the
Be sure all the necessary supplies are available to complete infusion from beginning to end. You will need VYJUVEK gel syringes, Hydrophobic dressing, clean scissors, standard dressing, gloves, biohazard container, 70% isopropyl alcohol pads, Virucidal agent and absorbent material for clean-up
Put on protective gloves

ADMINISTRATION

It may not be possible to treat all wounds each week. Because there is a maximum weekly dose of VYJUVEK, wound treatment prioritization may be required. VYJUVEK gel should be applied to wounds until they are closed before selecting new wound(s) to treat. Weekly treatment of previously treated wounds should be prioritized if they reopen

Take baseline vitals and document basic assessment
Wounds should be clean before applying VYJUVEK gel
- Remove any medicines, ointments, drainage, scabbing and dead skin at the wound area (bathing is not required)
The administration syringe should be primed prior to the initial application by pulling the plunger down and gently pushing it upwards, so that a small droplet of VYJUVEK gel forms at the tip of the syringe
Apply VYJUVEK gel to the selected wound(s) in droplets spaced evenly within the wound, approximately 1 cm-by1 cm apart (width of a fingertip). The resulting droplet pattern should loosely resemble a grid. Avoid touching the administration syringe directly to the wound, only the droplet will touch the wound
- Note: You can treat the wound underneath the blister cap after it has been drained. Additionally, the VYJUVEK gel can be applied directly to the hydrophobic dressing in the same 1 cm-by-1 cm pattern to the size of the wound, if direct administration is difficult
Use the scissors to cut the hydrophobic dressing to a size slightly larger than the wound and place the dressing atop the VYJUVEK gel droplets
Use the scissors to cut the standard dressing to a size slightly larger than the hydrophobic dressing and place the standard dressing atop the hydrophobic dressing
The VYJUVEK gel dressing should be left in place until the next dressing change. Disinfect VYJUVEK gel dressings, place in a sealable bag and discard into the household waste. Continue with your standard of care routine
Monitor patient for any adverse reactions
Record vitals 5-10 minutes post
Record lot numbers and expiration dates for syringe(s) used
Clean all surfaces that may have come in contact with VYJUVEK gel and treat all spills (blot using absorbent material) with a virucidal agent such as 70% isopropyl alcohol, 6% hydrogen peroxide, or <0.4% ammonium chloride
Dispose all materials (e.g., used and unused syringe (expired), cleaning materials) that may have come in contact with VYJUVEK gel into a biohazard container. Once the VYJUVEK gel dressings are removed and disinfected with a virucidal agent, place them in a sealable bag and discard into the household waste. Standard of care routine can then be continued.

ADDITIONAL INFO

HCP Website: VyjuvekHCP

Prescribing Info: Vyjuvek-PI

Administration Guide: Vyjuvek-Instructions for Use